2000–2001[]
In 2000 and 2001, the conference was referred to as the Central Division when Major League Soccer briefly reorganized into three divisions.
| Western Conference: Austin FC | Colorado Rapids | FC Dallas | Houston Dynamo | LA Galaxy | Los Angeles FC | Minnesota United | Portland Timbers | Real Salt Lake | San Jose Earthquakes | Seattle Sounders | Sporting Kansas City | St. Louis City | Vancouver Whitecaps Eastern Conference: Future clubs: Former clubs: Abandoned expansion: Related:  |