This series aired from September 11, 2000 to February 11, 2008.
Abby | All of Us1 | As If | The Bad Girl's Guide | Between Brothers | Clueless | Cuts | DiResta | Eve | Everybody Hates Chris1 | Family Rules | Girlfriends1 | Good News | Grown Ups | Guys Like Us | Half & Half | Head Over Heels | Hitz | Homeboys in Outer Space | The Hughleys | In the House | Love, Inc. | Love Boat: The Next Wave | Malcolm & Eddie | Moesha | The Mullets | One on One | The Parkers | Pig Sty | Platypus Man | Power Play | The Random Years | Reunited | Rock Me Baby | Second Time Around | The Secret Diary of Desmond Pfeiffer | Shasta McNasty | Social Studies | Sparks | Sweet Valley High
Drama/Sci-fi: All Souls | The Beat | Buffy the Vampire Slayer | The Burning Zone | Deadly Games | Freedom | Haunted | Jake 2.0 | Kevin Hill | Legacy | Legend | Level 9 | Live Shot | The Love Boat: The Next Wave | Marker | Mercy Point | Nowhere Man | Platinum | Roswell | Secret Agent Man | The Sentinel | Seven Days | Sex, Love & Secrets | South Beach | Special Unit 2 | Star Trek: Enterprise | Star Trek: Voyager | The Strip | Swift Justice | The Twilight Zone | Veronica Mars1 | The Watcher
Games show/Reality: America's Greatest Pets | America's Next Top Model1 | Amish in the City | Britney & Kevin: Chaotic | Chains of Love | Get This Party Started | I Dare You!: The Ultimate Challenge | Iron Chef USA | Manhunt | R U the Girl? | The Road to Stardom with Missy Elliott | Under One Roof
Sports: WWF/WWE SmackDown!1 | XFL
Cartoon/Animations: Bureau of Alien Detectors | Dilbert | Game Over | Gary & Mike | Home Movies | The Incredible Hulk | Jumanji | The Mouse & The Monster | Space Strikers
Former programming blocks:' UPN Weekend Morning Blocks
1Moved to The CW Television Network for the 2006-07 television season.
100 Days to Indy | ACC on the CW | All American | All American: Homecoming | Children Ruin Everything | Criss Angel's Magic with the Stars | Devils | FBoy Island (season 3) | Family Law | Fight to Survive | The Great American Joke Off | Inside the NFL (season 47) | Killer Camp | LIV Golf | Masters of Illusion (seasons 4-12) | Moonshine | Mysteries Decoded | Penn & Teller: Fool Us (seasons 2-10) | Recipe for Disaster | Superman & Lois | Totally Weird and Funny | Whose Line Is It Anyway? (2013) (seasons 9-20) | Wild Cards | World's Funniest Animals |
Upcoming programming: 61st Street (season 2) | Crime Nation | The Conners | Ride | Son of a Critch (season 3) | WWE NXT | NASCAR on The CW (NASCAR Xfinity Series)
Former programming: The 100 | 13: Fear is Real | 18 to Life | 4400 | 4Real | 7th Heaven2 | 90210 | Aliens in America | All of Us1 | America's Next Top Model1 | Arrow | A Wicked Offer | Batwoman | The Beautiful Life: TBL | Beauty & the Beast | Beauty and the Geek2 | The Bill Cunningham Show | Black Lightning | Breaking Pointe | Burden of Truth | Capture | The Carrie Diaries | The Catalina | Cedric's Barber Battle | Charmed | Containment | Crazy Ex-Girlfriend | Crowned: The Mother of All Pageants | Cult | CW Now | DC's Legends of Tomorrow | Dynasty | Easy Money | Emily Owens, M.D. | Everybody Hates Chris1 | Famous in 12 | Farmer Wants a Wife | The Flash | Fly Girls | Frequency | The Game | Gilmore Girls2 | Girlfriends1 | Gossip Girl | Gotham Knights | Greatest Geek Year Ever: 1982 | H8R | Hart of Dixie | Hellcats | Hidden Palms | High Society | Hitched or Ditched | Hooten & the Lady | In Harm's Way | In the Dark | iZombie | Jane the Virgin | Judge Jeanine Pirro | Katy Keene | Kung Fu | The L.A. Complex | Legacies | Legends of the Hidden Temple | Life is Wild | Life Sentence | Life Unexpected | Lifechangers | MAD TV | March | Melrose Place | The Messengers | Nancy Drew | Naomi | The Next: Fame is at Your Doorstep | Nikita | No Tomorrow | Oh Sit! | One Tree Hill2 | Online Nation | The Originals | The Outpost | Pandora | Perfect Score | Plain Jane | Privileged | Pussycat Dolls Present (The Search for the Next Doll | Girlicious) | Reaper | Reba2 | Reign | Remodeled | The Republic of Sarah | Ringer | Riverdale | The Robert Irvine Show | Roswell, New Mexico | Runaway | The Secret Circle | Seed | Shedding for the Wedding | Significant Mother | Smallville2 | Star-Crossed | Stargirl3 | Stylista | Supergirl | Supernatural2 | Swamp Thing3 | Tom Swift | The Tomorrow People | Two Sentence Horror Stories | The Tyra Banks Show | Valentine | Valor | The Vampire Diaries | Veronica Mars1 | Walker | Walker: Independence | The Winchesters | Would I Lie to You? | WWE Friday Night SmackDown1
Current programming blocks: One Magnificent Morning
Defunct programming blocks: Kids' WB | The CW4Kids | Toonzai | Vortexx
1Television program was carried over from UPN. 2Television program was carried over from The WB. 3Television program was carried over from DC Universe Infinite.