The station, originally owned by the TV Company of America, Inc., signed on the air for the first time on May 4, 1956 as KSHO-TV. Before then, ABC had been relegated to off-hours clearances on NBC affiliate KLRJ/KORK-TV (VHF channel 2, now KSNV on VHF channel 3) and CBS affiliate KLAS-TV (VHF channel 8).
1960–1964[]
1964-1968[]
1968–1972[]
1972–1977[]
1977–1980[]
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In 1979, KSHO was purchased by The Milwaukee Journal Company; the acquisition made it Journal's second television station property (and its first television station acquisition outside of the company's headquarters of Milwaukee). The station changed its callsign to the current KTNV-TV on March 2, 1980 (the -TV suffix was removed from 1988 to 2009).
On July 30, 2014, it was announced that the E. W. Scripps Company would buy Journal Communications in an all-stock transaction. Scripps would retain the two companies' broadcast properties, including KTNV, and spin-off its print properties as part of Journal Media Group, which was later acquired by Gannett, owner of KPNX in Phoenix, Arizona in 2016.
1KZTV is owned by SagamoreHill Broadcasting, but it is programmed and operated by Scripps under a Shared Services Agreement. 2WFLX is owned by Gray Television, but is programmed and operated by Scripps under a Shared Services Agreement.