When the company first opened in 1849, it was formally known as Charles Pfizer & Co., Inc., and began with a monochrome, ornate, circular logo with stylized, linked initials and much internal text, consistent with the common corporate aesthetic of the time.
In 1948, the company, now renamed Pfizer Corp. and nearing its centennial year of operation, decided to create a simpler, more modern-looking logo. This was the first step toward the most widely used and recognized logo of Pfizer until 2021. The longitude and latitude lines of a globe suggest the company's international reach and scope. This also marks the first time color was used in the logo.
Within two years of the globe logo being first unveiled, Pfizer decided to simplify it still further, removing the lines and making the logo a single color, and turning the letters white. Variants of blue would be established as the company's official corporate color from here on in.
In 1990, the logo was updated by having the "f" in Pfizer continue out of the oval and simplifying the other letters' shapes, as well as lightening the blue color. The oval is also a quarter taller than its predecessor, while maintaining the same overall width.
On January 5, 2021, Pfizer made its first major logo revamp since 1948, eliminating the oval entirely, turning the letters dark blue and adding a graphic suggestive of a DNA helix, reflecting the company's emphasis on cutting-edge medical/pharmaceutical research. This is also the first time since the 1948 logo that two distinct, separate color shades were used.