Woolco may refer to:
- Woolco (United States), American discount department store chain owned by F.W. Woolworth. The first location opened on June 6, 1962, and all stores were shuttered by January 1983.
- Woolco (Canada), discount department store chain owned by F.W. Woolworth’s Canadian division. The first location opened on August 15, 1962. 122 remaining stores were sold to Walmart in 1994, creating Walmart Canada.
- Woolco (UK), discount department store chain owned by F.W. Woolworth’s UK division. The first location opened on October 10, 1967, and the remaining 12 stores were sold to The Dee Corporation in 1986.
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